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Compatibility Awareness Key To Avoiding Sickle Offspring

The Red blood cell becomes sickle in shape because of the disorder in the gene of the patients, causing the red blood cells to break down and die quickly. Sickle cell disease is a genetic disorder that is inheritable from parent to offspring. This is identified by the irregular shape of the red blood cell as a sickle "S" which is different from a regular and normally shaped red blood cell which is round. It causes the expenditure of money, time, and energy in maintaining or taking care of the patient. 

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Hence the need for genotype testing or comparability testing of genetic makeup before marriage or any sexual intercourse. Such as the "AS" genotype of both parties is not compatible as this is the widely known cause of Sickle cell anemia or disease. 

There are two major types of sickle cell disease, which is the hemoglobin SS also called HbSS in which the child inherits the sickle cell gene "S" from both parents. The second type is called hemoglobin "SC" in which the child inherits the "S" sickle cell gene from one parent and inherits another hemoglobin defective gene "C" from the other parent. 

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Symptoms such as fatigue, sudden pains in the chest, pains in another region of the body, dizziness, blood level reduction, low oxygen level, are triggered by exposure to cold air, wind, and water, this is called the sickle cell crisis. The only known treatment is a bone marrow transplant from a compatible donor. Bone marrow is a part of the body system that contains blood stem cells that can become red blood cells, white blood cells, or platelets. 

Content created and supplied by: Dr-Kikiope (via Opera News )

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