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3 Types Of Sickle Cell Disease

1. Sickle Beta-Plus Thalassemia

Both beta-globin genes are substituted in people with Sickle Beta Thalassemia (SB) illness. The amount of normal beta-globin generated determines the severity of the condition.

Sickle Beta Thalssemia

The symptoms are essentially comparable to sickle cell anemia when no beta globin is produced, with severe cases requiring constant blood transfusions. Mediterranean and Caribbean heritage populations have a higher prevalence of Sickle Beta-Thalassemia.

2. Sickle Hemoglobin-D Disease

Hemoglobin D, a distinct substitution of the beta-globin gene, has been discovered to interact with the sickle hemoglobin gene through research.

Aldridge – RootStories

Anemia is somewhat severe in those with Sickle Hemoglobin-D disease (SD), and pain episodes are common. People of Asian and Latin American ancestry have a higher prevalence of Sickle Hemoglobin-D illness.

3. Sickle Hemoglobin-O Disease

Hemoglobin O, another form of beta-globin gene replacement, interacts with sickle hemoglobin. Sickle cell anemia symptoms can occur in people who have Sickle Hemoglobin-O illness (SO).

My first graphical abstract on the molecular basis of sickle cell anemia,  any tips for improvement?: Biochemistry

People of Arabian, North African, and Eastern Mediterranean heritage have a high prevalence of Sickle Hemoglobin-O illness.

Content created and supplied by: Dr-Kikiope (via Opera News )

Asian Latin American Sickle Beta-Thalassemia Sickle Hemoglobin-D beta-globin


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