Sickle cell anemia as the name suggests is such that there is a decrease in blood level and therefore the body of the patients experiences constant dizziness (loss of stability), fatigue (excessive tiredness), pale skin (loss of original skin color), which is due to the presence of the sickle cell gene in a pair ‘SS’ in the blood cells.
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Sickle cell anemia causes depletion of blood components rapidly. These blood cells such as the white blood cells, plasma, platelets, and red blood cells get affected. It does this by the restriction of the body’s organ which is responsible for the production of new blood cells. This organ is called the Bone Marrow, the bone marrow contains stem cells which can be either of the above-mentioned blood cells.
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The bone marrow secretes these stem cells into the body system to the site of production of the new blood cells. A sickle cell which is the red blood cell shaped like a sickle then causes depletion in these blood cells in volumes needed by the body. The white blood cell (WBC) is the cell responsible for fighting against infections; it is the body’s war mechanism against foreign materials that enter into the body system through the bloodstreams.
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The decrease in its production after undergoing apoptosis which is the word for cell programmed death, there are no new cells being produced and therefore this weakens the body’s ability to fight off or defend against infections.
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The plasma is the watery part of the blood that also contains blood cells, this allows for cell buoyancy, and with a decrease in its production cells' movement becomes restricted, and thus certain cells do not get to the site they are needed to carry out specific functions.
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The platelets are a small round thin blood cell that stops blood flow after a cut, it becomes thick and sticky that is to clot to cover up the surface of the wound, with a decrease in production after undergoing apoptosis, blood is lost in many volumes after a cut or injury with the inability of the blood to clot. Hence the need to identify the sickle cell gene early.
Content created and supplied by: Dr-Kikiope (via Opera News )
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