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Congenital Analgesia Is The Inability To Feel Pain. Those Affected Might Easily Die In Childhood.

One of the characteristics of living things is "Irritability" which is simply the ability of living things to respond to stimulus, which in the same vein, enables humans to respond to pain. But there are exceptions to this, in cases where certain individuals can not feel or respond to pain. This particular case in which one is not able to feel pain is called Congenital Insensitivity to pain or Congenital analgesia.

Congenital insensitivity to pain or congenital analgesia, is a rare condition in which a person cannot feel or has never felt physical pain. Congenital analgesia is an extremely dangerous condition, because it is common for people with the condition to die in childhood due to injuries or illnesses going unnoticed. Burn injuries are among the more common injuries.

Because children and adults with the disorder cannot feel pain, they may not respond to problems, thus being at a higher risk of more severe diseases.


It may be that the condition is caused by increased production of endorphins in the brain. Endorphins are any of a group of hormones secreted within the brain and nervous system and having a number of physiological functions. Endorphins play a major role in the body's inhibitory response to pain.

Research also showed; CIPA (Congenital Insensitivity to Pain and Anhidrosis) is a very rare genetic disease that causes the person to not feel pain, and have a lack of sweat glands. The lack of sweat glands leaves the person without the ability to maintain temperature and cool the body.

CIPA is a autosomal recessive disorder, meaning both parents need to be carriers of this disease for a person to have it. It is caused by the mutations of the NTRK1 gene.

Fact to Note:

Epidemiology shows that this case of Congenital insensitivity to pain is found in Vittangi, a village in Kiruna Municipality in northern Sweden , where nearly 40 cases have been reported.

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Ref: Wikipedia.

Content created and supplied by: SamGraced (via Opera News )


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