Sickle cell anemia or sickle cell disease is an inheritable genetic disorder that produces a defective red blood cell shape which then causes a constriction or a blockage in blood flow around the whole body system. With its distorted shape, the red blood cell restricts the movement of blood around the body by serving as a stopper with only a small opening or passageway around the cell in the vein and also the arteries which are the organs responsible for blood flow. This then causes the body to receive in smaller amounts and frequency the blood needed to carry out the necessary bodily functions.
Photo Credit: Nigeria Galleria
The inadequacy in the level of blood flow in the body systems makes it carry out its well-known processes less easily and less fast compared to its usual way of activity, therefore an imbalance is created.
Photo Credit: Johns Hopkins Medicine
One of the results of blood flow restriction is the accumulation of blood in a part or some parts of the body that causes tremendous pain such as the chest region and the knee region which causes the patient to be unable to move freely and breathing is also affected.
Photo Credit: MedlinePlus
This disease doesn’t get better over the course of years of the life of the patient, it can only be controlled by certain regulators which can over time increase the length of life in years, and instead, it gets much worse over time.
Photo Credit: Augusta University
The red blood cell with the sickle cell shape has the tendency to go through apoptosis which is known as the programmed cell death, in which the cells die after a set time or days or years that have been embedded into the cell itself, to enhance the production of new and better cells which would be more effective in carrying out certain body processes, and in this case, these red blood cells go through this process much faster and quicker.
Photo Credit: ResearchGate
This leads to a decrease in red blood cell count and with a restriction of blood flow there is less production of new ones by the organ responsible for blood cells production. And with a decrease in red blood cell count and less blood flow, there is a decrease in blood level which then causes anemia, which is a condition that is characterized by the low level of blood in the body and is seen by a noticeable pale skin round the eye region, tongue region, hand region, and the feet region also.
Content created and supplied by: Dr-Kikiope (via Opera News )
Opera News is a free to use platform and the views and opinions expressed herein are solely those of the author and do not represent, reflect or express the views of Opera News. Any/all written content and images displayed are provided by the blogger/author, appear herein as submitted by the blogger/author and are unedited by Opera News. Opera News does not consent to nor does it condone the posting of any content that violates the rights (including the copyrights) of any third party, nor content that may malign, inter alia, any religion, ethnic group, organization, gender, company, or individual. Opera News furthermore does not condone the use of our platform for the purposes encouraging/endorsing hate speech, violation of human rights and/or utterances of a defamatory nature. If the content contained herein violates any of your rights, including those of copyright, and/or violates any the above mentioned factors, you are requested to immediately notify us using via the following email address operanews-external(at)opera.com and/or report the article using the available reporting functionality built into our Platform See More