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Root Cause Of Anemia

Sickle cell anemia or sickle cell disease is an inheritable genetic disorder that produces a defective red blood cell shape which then causes a constriction or a blockage in blood flow around the whole body system. With its distorted shape, the red blood cell restricts the movement of blood around the body by serving as a stopper with only a small opening or passageway around the cell in the vein and also the arteries which are the organs responsible for blood flow. This then causes the body to receive in smaller amounts and frequency the blood needed to carry out the necessary bodily functions. 

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Photo Credit: Nigeria Galleria

The inadequacy in the level of blood flow in the body systems makes it carry out its well-known processes less easily and less fast compared to its usual way of activity, therefore an imbalance is created. 

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Photo Credit: Johns Hopkins Medicine

One of the results of blood flow restriction is the accumulation of blood in a part or some parts of the body that causes tremendous pain such as the chest region and the knee region which causes the patient to be unable to move freely and breathing is also affected. 

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Photo Credit: MedlinePlus

This disease doesn’t get better over the course of years of the life of the patient, it can only be controlled by certain regulators which can over time increase the length of life in years, and instead, it gets much worse over time. 

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Photo Credit: Augusta University

The red blood cell with the sickle cell shape has the tendency to go through apoptosis which is known as the programmed cell death, in which the cells die after a set time or days or years that have been embedded into the cell itself, to enhance the production of new and better cells which would be more effective in carrying out certain body processes, and in this case, these red blood cells go through this process much faster and quicker. 

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Photo Credit: ResearchGate

This leads to a decrease in red blood cell count and with a restriction of blood flow there is less production of new ones by the organ responsible for blood cells production. And with a decrease in red blood cell count and less blood flow, there is a decrease in blood level which then causes anemia, which is a condition that is characterized by the low level of blood in the body and is seen by a noticeable pale skin round the eye region, tongue region, hand region, and the feet region also. 

Content created and supplied by: Dr-Kikiope (via Opera News )

Johns Hopkins Medicine MedlinePlus

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