Sign in
Download Opera News App



Health Living


Disease prevention and treatment

Splenic Anomalies Of Sickle Cell Disease Patients

The spleen of sickle cell disease patients tends to differ from the normal spleen in areas such as shape, number, size, and location that is due to an aberrant embryologic development in the spleen. 

The spleen is attached to the posterior abdominal wall by two fatty ligaments one of which is the gastrosplenic ligament which connects the greater curvature of the stomach to the ventral aspect of the spleen, and the second is the splenorenal ligament which is found between the left kidney and the spleen. The spleen is located in the upper quadrant with a smooth serosal surface. 

E:\Articles\New folder (11)\download.jpeg

Photo Credit: Hindawi

An anomaly of the spleen with respect to shape is the presence of clefts, notches, and lobulations. Location in spleen anomaly is wandering spleen seen as the accessory spleen and small spleen. The number anomaly is seen as polysplenia and asplenia. The size anomaly is seen as splenomegaly, atrophy. Multiple lesions anomaly is seen as trauma, infections, joint hemangiomas, and hematomas.  Polysplenia is characterized by multiple small accessory spleens, rather than the normal single, full-sized spleen. 

E:\Articles\New folder (11)\images (19).jpeg

Photo Credit: ResearchGate

It sometimes occurs on its own or it is often accompanied by other developmental abnormalities of the spleen or that affect the spleen. Asplenia is the complete absence of the spleen. Asplenia can be an anatomic absence of the spleen or functional asplenia secondary to a variety of different disease states. Splenosis is an acquired spleen anomaly that occurs in cases of splenic trauma or splenectomy (surgical removal of the spleen). 

E:\Articles\New folder (11)\images (18).jpeg

Photo Credit: Oncohema Key

Small spleen, adults with sickle cell disease usually have a homozygous sickle cell gene that causes a chronic splenic infarction. The accessory spleen is also a spleen anomaly that is seen as a small nodule of splenic tissue that is found apart from the main body of the spleen. 

E:\Articles\New folder (11)\images (17).jpeg

Photo Credit: Plastic Surgery key

Magnetic resonance imaging is efficient and sought a method for spleen anomalies in sickle cell disease patients. 

E:\Articles\New folder (11)\images (16).jpeg

Photo Credit: Plastic Surgery Key

Content created and supplied by: Dr-Kikiope (via Opera News )

Hindawi Sickle Cell


Load app to read more comments