Female genital atresia is a rare condition in which the lower portion of the genital has not formed as it should. The lower portion of the genital may instead consist of fibrous tissue, which can cause a blockage. A person with genital atresia will still have ovaries and a uterus, although they may be underdeveloped.
According to Medicalnewstoday, the female genital is the muscular tube that leads from the external genitals, or vulva, to the cervix of the uterus.
A person may not be aware that they have genital atresia until they reach puberty and do not begin menstruating despite having all other signs of puberty.
What is genital atresia?
According to a 2018 case report, genital atresia is a rare condition affecting 1 in 4,000 - 10,000 people. Some people also use the term genital agenesis to describe this condition, although the two conditions have differences.
However, there is no universal system to classify this condition, making identification difficult.
A 2020 case study notes that during fetal development, the Müller’s ducts form the fallopian tubes, the uterus, and the upper, or proximal, two-thirds of the genital.
The lower, or distal, portion of the genital develops from the urogenital sinus, a part of the body that is present during the development of the reproductive and urinary organs.
Genital atresia occurs when the urogenital sinus fails to form the lower portion of the genital.
Instead, a plug of fibrous tissue may block the genital opening. Behind the plug of tissue, the genital can be shorter or missing. There may also be no connection between the upper and lower part of the genital.
The genital changes are internal. As a result, external genitalia, or vulva, remains unaffected.
The condition usually occurs as a result of the following syndromes:
1. Bardet-Biedl syndrome
2. Fraser syndrome
3. Mayer-Rokitansky-Küster-Hauser syndrome (MRKH).
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