Sevilla vs Borussia Dortmund
Sevilla have been in stunning form in recent weeks, winning their last nine matches, and will be confident of extending that run on Wednesday night. The LaLiga side haven't failed to win a home game in 2021 and won't fear an out of sorts Borussia Dortmund in midweek.
The Bundesliga side have been underwhelming of late, winning just two of their last seven, one of which came against lower league opposition Paderborn in the DFB-Pokal. Edin Terzic has overseen three successive away league defeats, and that doesn't bode well for a daunting trip to Seville.
Given Sevilla's excellent performances in recent weeks, the home side should earn a huge first leg win, but given Borussia Dortmund's firepower, it wouldn't be a surprise to see them return to Germany with a lifeline.
FC Porto vs Juventus
Porto come into their Champions League meeting with Juventus on a four-game drawing run. That said, the Portuguese side have lost just one of their last 25 competitive matches and have lost just once at home this season.
Juventus' form has steadily improved under the watchful eye of Andrea Pirlo, however they face Porto off the back of a 1-0 defeat at the hands of Napoli. The Old Lady took on Porto at this stage of the 2016/17 Champions League, securing a 3-0 aggregate win in the process.
Porto are without key men down their left flank and if Juventus can maximise the absence of Sanusi and Otavio, then they have the means to secure a first leg advantage on Wednesday night.
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