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sickle cell

HEALTH

Splenic Anomalies Of Sickle Cell Disease Patients

The spleen of sickle cell disease patients tends to differ from the normal spleen in areas such as shape, number, size, and location that is due to an aberrant embryologic development in the spleen. The spleen is attached to the posterior abdominal wall by two fatty ligaments one of which is the gastrosplenic ligament which connects the greater curvature of the stomach to the ventral aspect of the spleen, and the second is the splenorenal ligament which is found between the left kidney and the spleen.

  3 months ago ago
Splenic Anomalies Of Sickle Cell Disease Patients

HEALTH

Sickle Cell Disease In Hyperplasia

Hyperplasia is seen as an increased number of cells resulting in the increase in mass of tissue or organ affected in sickle cell disease patients. Hyperplasia is a condition that allows for the enlargement of an organ or tissue caused by an increase in the amount of organic tissue that results from cell proliferation.

  3 months ago ago
Sickle Cell Disease In Hyperplasia

HEALTH

Embolism In Sickle Cell Disease

Embolism is a sudden blockage of an artery in a sickle cell disease patient. The common types of embolism is pulmonary embolism, arterial embolism, and air embolism, brain embolism, retinal embolism, septic embolism, amniotic embolism, fat embolism. Pulmonary embolism is a condition that is described by the blockage of one or more arteries in the lungs by blood clot, the embolus is formed in the leg, (and this is sometimes known as deep vein thrombosis DVT), lodges in one of the arteries of the lungs.

  3 months ago ago
Embolism In Sickle Cell Disease

HEALTH

Macrovascular Dysfunction In Sickle Cell Disease

Macrovascular dysfunction or macrovascular disease in sickle cell disease patients is characterized by the disease of the large or macro blood vessels in the body. This large blood vessel includes the aorta, the coronary arteries, peripheral arteries, cerebrovasculature, and the sizable arteries in the brain and in the limbs.

  3 months ago ago
Macrovascular Dysfunction In Sickle Cell Disease

HEALTH

Organ Damage In Sickle Cell Disease

Organ damage is referred to as the damage occurring in major organs of sickle cell disease patients causing a malfunction of the body’s systems. Due to decreased levels of blood flow and supply and oxygen to the organs, they begin to weaken and may eventually die.

  3 months ago ago
Organ Damage In Sickle Cell Disease

HEALTH

Pulmonary Hypertension In Sickle Cell Disease

Pulmonary hypertension also written as PH, is a type of high blood pressure in sickle cell disease that affects the arteries in the lungs and in the heart (especially the right side) of sickle cell disease patients. Pulmonary hypertension occurs when the pressure in the blood vessels leading from the heart to the lungs is too high.

  3 months ago ago
Pulmonary Hypertension In Sickle Cell Disease

HEALTH

Pathophysiology Of Sickle Cell Disease

Pathophysiology of sickle cell disease has to do it with its adverse effects and protean or variable complications, which has led to recent advances that are targeted towards molecular therapies for sickle cell disease patients. In sickle cell disease, a single amino acid substitution in the beta-globin β-globin chain leads to the polymerization of the mutant hemoglobin S that leads to the impairment of the erythrocyte (red blood cells) rheology and survival.

  3 months ago ago
Pathophysiology Of Sickle Cell Disease

HEALTH

Stroke Complication In Sickle Cell Disease

Stroke is developed in sickle cell disease patients when there is an interruption to blood supply or reduction in obtaining oxygen and nutrient to a part of the brain. Stroke is cerebrovascular disease and thus is also called the cerebrovascular accident CVA. This means stroke affects the blood vessels that feed the brain oxygen, and when the brain does not receive adequate oxygen, damage starts to occur.

  3 months ago ago
Stroke Complication In Sickle Cell Disease

HEALTH

Splenomegaly In Sickle Cell Disease

Splenomegaly in sickle cell disease or sickle cell anemia is described as the palpitation of the spleen below the costal margin in quiet respiration. Splenomegaly occurs in patients with sickle cell disease when they are around ten (10) years of age. Persistent splenomegaly is often rare in children older than ten years.

  3 months ago ago
Splenomegaly In Sickle Cell Disease

HEALTH

Pulmonary Edema In Sickle Cell Disease

Pulmonary edema is a complication of sickle cell disease that affects the management of sickle cell crises. The use of vigorous fluid replacement with hypotonic saline and parenteral narcotic analgesics are conventional modalities of therapy in sickle cell crisis management but are likely to contribute to the development of pulmonary edema in sickle cell disease patients.

  3 months ago ago
Pulmonary Edema In Sickle Cell Disease

HEALTH

Osteoporosis In Sickle Cell Disease

The bone of the body is a living tissue that needs complete replacement at each point, this has to do with making new bones and removing old ones, but the sickle cell disease patient’s body cannot keep up with new bone production and old bone removal due to osteoporosis, causing severe damage to the limitation to bone function.

  3 months ago ago
Osteoporosis In Sickle Cell Disease

HEALTH

Atherosclerosis In Sickle Cell Disease

Atherosclerosis is the complication of sickle cell disease that is seen as the hardening or thickening of the arteries which is caused by a buildup of plaque in the artery's inner lining. It is a progressive disease that begins early as childhood in sickle cell disease patients. Plaque is a variety of materials containing cholesterol, fatty substances, waste products, calcium, and the clot-making substance fibrin that collects together on the artery walls, causing the narrowing and stiffening of arteries.

  3 months ago ago
Atherosclerosis In Sickle Cell Disease

HEALTH

How Sickle Cell Affects Red Bloods Cells

Sickle cell disease majorly affects the red blood cells of patients causing it to form a sickle-shaped like that of a half-moon and leads to blockage of blood flow and essential nutrients from the site of production to the site of action in the circulatory system through the whole body.

  3 months ago ago
How Sickle Cell Affects Red Bloods Cells

HEALTH

Cardiac Arrest In Sickle Cell

Sickle cell disease patients are known to experience this state as the severity of the condition worsens, it is described as the sudden, and also unexpected loss of the heart’s function, with no breathing state, and consciousness. It is usually a result of an electrical disturbance in the heart.

  3 months ago ago
Cardiac Arrest In Sickle Cell

HEALTH

Management Of Sickle Cell Disease

Sickle cell disease patients require proper care and have high maintenance needs to preserve life and control crises. The most well-known reason as to why patients with sickle cell disease are due to the severe and acute pain they experience and thus they require treatment and management. The variety of pain describes the variety of management procedures to be taken.

  3 months ago ago
Management Of Sickle Cell Disease

HEALTH

Osteotomy In Sickle Cell Disease

Osteotomy is the surgical procedure that involves the cutting of bones to either lengthen it or shorten it, or to do an alignment change, or for a reshape. The types of osteotomy could be a knee, tibia (shinbone), hip, jaw, chin, and femur (thighbone) osteotomy is done to relieve pressure on the knee joint.

  3 months ago ago
Osteotomy In Sickle Cell Disease

HEALTH

Hyperplasia In Sickle Cell Disease

Hyperplasia is a developed medical condition in sickle cell disease patients that is characterized by the enlargement of an organ or tissue which is caused by an increase in the amount of organic tissue that results from cell proliferation, this could also cause an increase in weight of organ or tissue.

  3 months ago ago
Hyperplasia In Sickle Cell Disease

HEALTH

Priapism Complication In Sickle Cell Disease

Priapism is a complication developed in sickle cell disease patients, in both children and adults that are males only. In patients with sickle cell disease, the sickling of red blood cells can cause an erection of the penis; this is the major cause of priapism. Picture Credit: Medscape Reference

  3 months ago ago
Priapism Complication In Sickle Cell Disease

SCIENCE-HIGHTECH

Genetic Testing In Prevention Of Sickle Cell Disease

Genetic testing is a type of blood testing used in the identification of the changes in deoxyribonucleic acid DNA or chromosome structure, it can also measure the results of genetic changes, such as the ribonucleic acid RNA analysis as an output of gene expression, or through biochemical analysis to measure specific output protein output, this requires taking a blood sample for testing.

  3 months ago ago
Genetic Testing In Prevention Of Sickle Cell Disease

HEALTH

Sickle Cell Disease – Avascular necrosis (Femoral Head)

It is a debilitating disease that requires doctors, caretakers, who are in charge of treating the sickle cell patients with developed avascular necrosis of the femoral head should be quite knowledgeable on what they ought to do and what they ought not to do, to prevent further compromising of the patient’s immune system.

  3 months ago ago
Sickle Cell Disease – Avascular necrosis (Femoral Head)